THAP11

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, THAP11 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible THAP11-associated genes across cancer lineages are CD4+ Tem. Each is linked with THAP11 in more than 1 cancer types. Because this analysis shows association rather than direction, both THAP11-to-partner and partner-to-THAP11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tem grouped by THAP11-low versus THAP11-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP11→partner) and Y-score (partner→THAP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMCD4+ Tem →+0.031+5.624<.001.03931
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD4+ Tem by THAP11 expression — SKCM

Box plot of CD4+ Tem in THAP11-low vs THAP11-high samples in SKCM.

Explore this box plot interactively →

Exploration