THAP11

Across TCGA cell cohorts, THAP11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,856 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible THAP11-associated GO terms across cancer lineages are mRNA alternative polyadenylation, Peptidyl-methionine modification, and Regulation of centromeric sister chromatid cohesion. Each is linked with THAP11 in more than 16 cancer types. Because this analysis shows association rather than direction, both THAP11-to-partner and partner-to-THAP11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA alternative polyadenylation grouped by THAP11-low versus THAP11-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP11→partner) and Y-score (partner→THAP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	mRNA alternative polyadenylation →	+0.091	+0.692	<.001	<.001	3	17
LUNG_SCLC	Peptidyl-methionine modification →	+0.214	+0.485	.004	<.001	3	17
STOMACH	Regulation of centromeric sister chromatid cohesion →	+0.161	+1.075	<.001	<.001	3	15
PANCREAS	Interstrand cross-link repair →	+0.100	+0.702	<.001	<.001	3	15
PANCREAS	Mitotic DNA replication →	+0.217	+0.639	<.001	<.001	3	15
LIVER	DNA strand elongation involved in DNA replication →	+0.175	+0.696	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,856 associations by consensus.

mRNA alternative polyadenylation by THAP11 expression — SKIN

Explore this box plot interactively →