THAP1

Across TCGA cell cohorts, THAP1 RNA expression is significantly associated with the RNA expression of many other genes, with 8,318 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible THAP1-associated genes across cancer lineages are VDAC3, FNTA, and LSM1. Each is linked with THAP1 in more than 18 cancer types. Because this analysis shows association rather than direction, both THAP1-to-partner and partner-to-THAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THAP1 versus VDAC3 in BREAST, with a Pearson correlation of 0.82.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP1→partner) and Y-score (partner→THAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	VDAC3 →	+1.329	+0.807	<.001	<.001	3	19
BREAST	FNTA →	+1.216	+0.733	<.001	<.001	3	18
URINARY_TRACT	LSM1 →	+1.282	+0.817	<.001	<.001	3	16
BREAST	GOLGA7 →	+1.252	+0.699	<.001	<.001	3	15
BLOOD_Myeloma	HOOK3 →	+1.237	+0.604	<.001	<.001	3	15
LIVER	KAT6A →	+1.235	+0.708	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,318 associations by consensus.

THAP1 vs VDAC3 — BREAST

Explore this scatter interactively →