TGM7

Across TCGA patient cohorts, TGM7 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,416 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TGM7-associated GO terms across cancer lineages are Negative regulation of peptidase activity, DTMP metabolic process, and Pyrimidine nucleoside monophosphate metabolic process. Each is linked with TGM7 in more than 7 cancer types. Because this analysis shows association rather than direction, both TGM7-to-partner and partner-to-TGM7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of peptidase activity grouped by TGM7-low versus TGM7-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TGM7→partner) and Y-score (partner→TGM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of peptidase activity →	+0.078	+0.153	<.001	<.001	3	8
STAD	DTMP metabolic process →	+0.041	+0.097	<.001	<.001	3	8
STAD	Pyrimidine nucleoside monophosphate metabolic process →	+0.070	+0.165	<.001	<.001	3	8
STAD	Negative regulation of hydrolase activity →	+0.082	+0.156	<.001	<.001	2	8
ESCA	Icosanoid metabolic process →	+0.035	+0.200	<.001	<.001	3	7
ESCA	Epidermal cell differentiation →	+0.067	+0.199	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,416 associations by consensus.

Negative regulation of peptidase activity by TGM7 expression — STAD

Explore this box plot interactively →