TGM7

Across TCGA cell cohorts, TGM7 RNA expression is significantly associated with the go_rna of many other GO terms, with 451 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TGM7-associated GO terms across cancer lineages are Negative regulation of cell-substrate adhesion, Regulation of tumor necrosis factor superfamily cytokine production, and Chemorepulsion of axon. Each is linked with TGM7 in more than 3 cancer types. Because this analysis shows association rather than direction, both TGM7-to-partner and partner-to-TGM7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell-substrate adhesion grouped by TGM7-low versus TGM7-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TGM7→partner) and Y-score (partner→TGM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of cell-substrate adhesion →	+0.113	+0.005	.002	.007	2	4
BONE	Regulation of tumor necrosis factor superfamily cytokine production →	+0.094	+0.003	.001	.006	3	3
PANCREAS	Chemorepulsion of axon →	+0.224	+0.003	.009	.005	2	3
BLOOD_Leukemia	Pancreatic juice secretion →	-0.120	-0.040	.009	.009	3	2
OVARY	Complement activation, GZMK pathway →	+0.736	+0.386	.009	.005	3	2
OVARY	Endothelium development →	+0.056	+0.373	.003	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 451 associations by consensus.

Negative regulation of cell-substrate adhesion by TGM7 expression — BONE

Explore this box plot interactively →