TGM6

Across TCGA patient cohorts, TGM6 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,638 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TGM6-associated GO terms across cancer lineages are Microtubule polymerization, Regulation of macroautophagy, and Negative regulation of post-translational protein modification. Each is linked with TGM6 in more than 9 cancer types. Because this analysis shows association rather than direction, both TGM6-to-partner and partner-to-TGM6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule polymerization grouped by TGM6-low versus TGM6-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TGM6→partner) and Y-score (partner→TGM6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Microtubule polymerization →	+0.057	+0.162	<.001	<.001	3	10
STAD	Regulation of macroautophagy →	+0.064	+0.142	<.001	<.001	3	10
STAD	Negative regulation of post-translational protein modification →	+0.057	+0.128	<.001	<.001	3	10
STAD	Negative regulation of protein ubiquitination →	+0.058	+0.130	<.001	<.001	3	10
ESCA	Molting cycle →	+0.045	+0.453	<.001	<.001	3	10
STAD	Vesicle tethering →	+0.059	+0.125	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,638 associations by consensus.

Microtubule polymerization by TGM6 expression — STAD

Explore this box plot interactively →