TGM6

Across TCGA cell cohorts, TGM6 RNA expression is significantly associated with the mutation status of many other genes, with 123 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TGM6-associated genes across cancer lineages are DYNC2H1, CADPS, and ENAM. Each is linked with TGM6 in more than 1 cancer types. Because this analysis shows association rather than direction, both TGM6-to-partner and partner-to-TGM6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DYNC2H1 grouped by TGM6-low versus TGM6-high in URINARY_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TGM6→partner) and Y-score (partner→TGM6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	DYNC2H1 →	+4.050	+0.048	.002	<.001	3	2
URINARY_TRACT	CADPS →	+3.050	+0.030	.007	.002	3	2
BLOOD_Leukemia	ENAM →	+4.569	+0.015	.003	<.001	3	2
BLOOD_Leukemia	DTNB →	+5.569	+0.022	.001	<.001	3	2
BLOOD_Myeloma	HEATR3 →	+4.807	+0.006	.006	<.001	3	1
BLOOD_Myeloma	TMEM120B →	+4.807	+0.006	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 123 associations by consensus.

DYNC2H1 by TGM6 expression — URINARY_TRACT

Explore this box plot interactively →