TGM4

Across TCGA patient cohorts, TGM4 RNA expression is significantly associated with the RNA expression of many other genes, with 10,790 significant associations in total. ACC shows the largest number of these associations.

The most reproducible TGM4-associated genes across cancer lineages are ZDHHC3, COL7A1, and RFX8. Each is linked with TGM4 in more than 14 cancer types. Because this analysis shows association rather than direction, both TGM4-to-partner and partner-to-TGM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TGM4 versus ZDHHC3 in ACC, with a Pearson correlation of 0.29.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TGM4→partner) and Y-score (partner→TGM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	ZDHHC3 →	+0.988	+0.125	<.001	<.001	3	15
ESCA	COL7A1 →	+1.884	+0.364	<.001	<.001	3	13
LAML	RFX8 →	+1.804	+0.437	<.001	<.001	2	12
ESCA	FJX1 →	+1.121	+0.334	<.001	<.001	3	11
ACC	GEN1 →	+0.687	+0.141	<.001	<.001	3	11
ACC	KDM2A →	+0.862	+0.121	<.001	.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,790 associations by consensus.

TGM4 vs ZDHHC3 — ACC

Explore this scatter interactively →