TGM4

Across TCGA patient cohorts, TGM4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,982 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TGM4-associated GO terms across cancer lineages are Positive regulation of mitotic cell cycle, Regulation of embryonic development, and Positive regulation of mitotic cell cycle spindle assembly checkpoint. Each is linked with TGM4 in more than 14 cancer types. Because this analysis shows association rather than direction, both TGM4-to-partner and partner-to-TGM4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitotic cell cycle grouped by TGM4-low versus TGM4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TGM4→partner) and Y-score (partner→TGM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of mitotic cell cycle →	+0.062	+0.151	<.001	<.001	3	15
STAD	Regulation of embryonic development →	+0.059	+0.140	<.001	<.001	3	15
ACC	Positive regulation of mitotic cell cycle spindle assembly checkpoint →	+0.055	+0.133	<.001	.001	2	15
STAD	Obsolete ncRNA transcription →	+0.069	+0.157	<.001	<.001	3	14
STAD	Regulation of signal transduction by p53 class mediator →	+0.124	+0.203	<.001	<.001	2	15
ACC	Negative regulation of mitotic cell cycle phase transition →	+0.036	+0.125	<.001	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,982 associations by consensus.

Positive regulation of mitotic cell cycle by TGM4 expression — STAD

Explore this box plot interactively →