TGM4

Across TCGA cell cohorts, TGM4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,893 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TGM4-associated GO terms across cancer lineages are Primary alcohol metabolic process, Positive regulation of extracellular matrix organization, and Spliceosomal conformational changes to generate catalytic conformation. Each is linked with TGM4 in more than 8 cancer types. Because this analysis shows association rather than direction, both TGM4-to-partner and partner-to-TGM4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Primary alcohol metabolic process grouped by TGM4-low versus TGM4-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TGM4→partner) and Y-score (partner→TGM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Primary alcohol metabolic process →	-0.074	-0.199	<.001	.003	3	8
STOMACH	Positive regulation of extracellular matrix organization →	+0.123	+0.129	.009	.009	2	9
CNS	Spliceosomal conformational changes to generate catalytic conformation →	+0.056	+0.117	.003	.004	3	8
STOMACH	Regulation of extrinsic apoptotic signaling pathway →	+0.074	+0.125	.001	.006	3	8
OVARY	Regulation of apoptotic signaling pathway →	+0.046	+0.226	<.001	.002	3	7
OVARY	Regulation of nucleocytoplasmic transport →	+0.081	+0.222	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,893 associations by consensus.

Primary alcohol metabolic process by TGM4 expression — PANCREAS

Explore this box plot interactively →