TGIF2LY

Across TCGA pan-cancer cohorts, TGIF2LY Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TGIF2LY data layer compared with 8 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TGIF2LY Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TGIF2LY expression acts as an unfavorable survival marker.

LUAD, GBM, and MESO are the cancer types where TGIF2LY Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.079	0.812	<.001	24	view →
GBM	DFS	Median	All	0.043	0.257	<.001	12	view →
MESO	OS	Median	All	0.169	0.556	.043	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

TGIF2LY–LUAD (OS)

Open the LUAD breakdown →