TGFBRAP1

Across TCGA patient cohorts, TGFBRAP1 protein abundance is significantly associated with the RNA expression of many other genes, with 23,133 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TGFBRAP1-associated genes across cancer lineages are DCN, MAN1C1, and COLEC12. Each is linked with TGFBRAP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both TGFBRAP1-to-partner and partner-to-TGFBRAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TGFBRAP1 versus DCN in UCEC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFBRAP1→partner) and Y-score (partner→TGFBRAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DCN →	+1.364	+0.164	<.001	<.001	3	6
BRCA	MAN1C1 →	+0.842	+0.229	<.001	<.001	3	6
OV	COLEC12 →	+1.098	+0.213	<.001	.006	3	6
BRCA	SNED1 →	+0.959	+0.237	<.001	<.001	3	6
UCEC	DACT3 →	+1.010	+0.166	<.001	<.001	3	6
HNSC	GOLGA8N →	+0.414	+0.188	.002	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,133 associations by consensus.

TGFBRAP1 vs DCN — UCEC

Explore this scatter interactively →