TGFBR3L

Across TCGA pan-cancer cohorts, TGFBR3L RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated TGFBR3L data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher TGFBR3L RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TGFBR3L expression acts as an unfavorable survival marker, although some lineages such as SCLC and LIHC show a favorable association.

ACC, BLCA, and COAD are the cancer types where TGFBR3L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.284	0.865	<.001	131	view →
BLCA	DFS	Median	All	0.255	0.472	.001	83	view →
COAD	DFS	Tertile	II,III,IV	0.302	0.614	<.001	51	view →
SCLC	DFS	Median	III,IV	0.509	0.238	.011	40	view →
CHOL	DFS	Tertile	II,III,IV	0.140	0.708	.005	32	view →
READ	OS	Tertile	II,III,IV	0.827	0.982	.002	27	view →
UCS	DFS	Median	IV	0.367	0.952	.001	24	view →
LIHC	DFS	Median	All	0.600	0.483	.006	20	view →
THCA	DFS	Quartile	IV	0.543	1.000	.004	18	view →
UVM	OS	Quartile	All	0.948	0.551	.024	17	view →
MESO	DFS	Quartile	IV	0.213	0.609	.020	12	view →
LUSC	DFS	Tertile	II,III,IV	0.920	0.637	.013	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

TGFBR3L–ACC (DFS)

Open the ACC breakdown →