TGFBI

Across TCGA patient cohorts, TGFBI protein abundance is significantly associated with the protein abundance of many other proteins, with 36,909 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TGFBI-associated proteins across cancer lineages are SERPINA4, SERPINF1, and SRPX2. Each is linked with TGFBI in more than 9 cancer types. Because this analysis shows association rather than direction, both TGFBI-to-partner and partner-to-TGFBI results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TGFBI versus SERPINA4 in LSCC, with a Pearson correlation of 0.50.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFBI→partner) and Y-score (partner→TGFBI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SERPINA4 →	+0.583	+0.812	<.001	<.001	3	10
OV	SERPINF1 →	+0.824	+0.685	<.001	<.001	3	10
CCRCC	SRPX2 →	+0.965	+1.040	<.001	<.001	3	10
UCEC	ANGPTL2 →	+0.677	+0.481	<.001	<.001	3	10
CCRCC	HTRA1 →	+0.952	+0.890	<.001	<.001	3	10
GBM	ITGA5 →	+0.534	+0.895	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 36,909 associations by consensus.

TGFBI vs SERPINA4 — LSCC

Explore this scatter interactively →