TGFB3-AS1

Across TCGA pan-cancer cohorts, TGFB3-AS1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of TGFB3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where TGFB3-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types TGFB3-AS1 is over-expressed in tumor, although a few such as THCA and UCEC show the opposite, repressed pattern.

THCA, CHOL, and UCEC are the cancer types where TGFB3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TGFB3-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.074	.005	4	view →
CHOL	All	All	+0.224	.005	2	view →
UCEC	All	All	−0.182	.038	2	view →
LIHC	All	All	−0.031	.007	2	view →
LUSC	Female	All	−0.172	.031	1	view →
KICH	All	III,IV	−0.167	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

TGFB3-AS1–THCA

Open the THCA breakdown →