TGFB2

Across TCGA patient cohorts, TGFB2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,569 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TGFB2-associated proteins across cancer lineages are AFAP1, ENAH, and SULF1. Each is linked with TGFB2 in more than 5 cancer types. Because this analysis shows association rather than direction, both TGFB2-to-partner and partner-to-TGFB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TGFB2 versus AFAP1 in CCRCC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFB2→partner) and Y-score (partner→TGFB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	AFAP1 →	+0.468	+0.674	<.001	<.001	3	6
CCRCC	ENAH →	+0.383	+0.505	<.001	<.001	3	6
CCRCC	SULF1 →	+0.760	+0.451	<.001	<.001	3	6
BRCA	ACTN1 →	+0.524	+1.537	<.001	<.001	3	5
HNSC	AFAP1_S283 →	+0.618	+1.009	<.001	<.001	3	5
BRCA	CNN3 →	+0.541	+1.136	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,569 associations by consensus.

TGFB2 vs AFAP1 — CCRCC

Explore this scatter interactively →