TGFB2

Across TCGA patient cohorts, TGFB2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,820 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TGFB2-associated genes across cancer lineages are SYDE1, ISLR, and CLDN11. Each is linked with TGFB2 in more than 4 cancer types. Because this analysis shows association rather than direction, both TGFB2-to-partner and partner-to-TGFB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TGFB2 versus SYDE1 in BRCA, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFB2→partner) and Y-score (partner→TGFB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SYDE1 →	+0.741	+0.458	<.001	.007	3	4
CCRCC	ISLR →	+1.721	+0.865	.001	<.001	3	4
LSCC	CLDN11 →	+0.895	+0.724	<.001	<.001	3	4
CCRCC	PPP1R14A →	+0.970	+0.507	<.001	.003	3	4
BRCA	CAVIN1 →	+0.816	+0.551	<.001	<.001	3	4
CCRCC	CCN2 →	+1.254	+0.701	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,820 associations by consensus.

TGFB2 vs SYDE1 — BRCA

Explore this scatter interactively →