TGFB2-AS1

Across TCGA pan-cancer cohorts, TGFB2-AS1 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated TGFB2-AS1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher TGFB2-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated TGFB2-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and KIRC show a favorable association.

UCS, ACC, and MESO are the cancer types where TGFB2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Median	III,IV	0.530	0.139	<.001	106	view →
ACC	OS	Median	All	0.420	0.776	<.001	85	view →
MESO	OS	Median	All	0.281	0.485	.001	58	view →
LGG	DFS	Median	All	0.619	0.855	<.001	53	view →
LIHC	OS	Median	All	0.714	0.847	.008	39	view →
BLCA	OS	Quartile	All	0.548	0.702	.004	29	view →
KIRC	DFS	Median	All	0.796	0.488	<.001	27	view →
CESC	DFS	Quartile	All	0.749	0.879	.008	24	view →
COAD	DFS	Quartile	IV	0.640	0.223	.006	16	view →
LUSC	DFS	Tertile	II,III,IV	0.550	0.707	.019	16	view →
UCEC	DFS	Median	IV	0.839	0.535	.002	12	view →
KIRP	OS	Median	IV	0.045	0.590	.025	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

TGFB2-AS1–UCS (DFS)

Open the UCS breakdown →