TGFB2-AS1

Across TCGA pan-cancer cohorts, TGFB2-AS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of TGFB2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where TGFB2-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types TGFB2-AS1 is over-expressed in tumor, although a few such as KICH and LUAD show the opposite, repressed pattern.

KICH, LUAD, and LIHC are the cancer types where TGFB2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TGFB2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−1.023	<.001	7	view →
LUAD	Female	All	−0.987	<.001	6	view →
LIHC	All	All	+0.395	<.001	6	view →
LUSC	Female	All	−0.927	.007	4	view →
STAD	All	II,III,IV	+0.776	.005	4	view →
COAD	Female	All	+0.321	.003	4	view →
CHOL	All	All	+2.515	<.001	3	view →
UCEC	All	All	−0.878	.009	2	view →
KIRP	All	All	−0.498	.003	2	view →
PRAD	All	All	−0.430	.040	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

TGFB2-AS1–KICH

Open the KICH breakdown →