Across TCGA patient cohorts, TGFA-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,782 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TGFA-IT1-associated proteins across cancer lineages are SCEL_S312, SERPINB5, and SFN. Each is linked with TGFA-IT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TGFA-IT1-to-partner and partner-to-TGFA-IT1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFA-IT1→partner) and Y-score (partner→TGFA-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SCEL_S312 →	+0.994	+0.743	<.001	<.001	3	3
LSCC	SERPINB5 →	+1.174	+0.883	<.001	<.001	3	3
UCEC	SFN →	+0.774	+0.779	<.001	<.001	3	3
UCEC	EVPL →	+0.656	+0.960	.002	.001	3	3
UCEC	KIAA1671_S366 →	+0.849	+0.882	.001	.007	3	3
LSCC	KRT16_S448 →	+1.892	+0.917	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,782 associations by consensus.

Exploration

TGFA-IT1 survival (RNA) · tumor vs normal (RNA) · all TGFA-IT1 data types