Across TCGA patient cohorts, TGFA-IT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,273 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TGFA-IT1-associated GO terms across cancer lineages are Positive regulation of post-translational protein modification, Positive regulation of protein modification by small protein conjugation or removal, and Regulation of signal transduction by p53 class mediator. Each is linked with TGFA-IT1 in more than 16 cancer types. Because this analysis shows association rather than direction, both TGFA-IT1-to-partner and partner-to-TGFA-IT1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TGFA-IT1→partner) and Y-score (partner→TGFA-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Positive regulation of post-translational protein modification →	+0.056	+0.055	<.001	<.001	3	17
UCEC	Positive regulation of protein modification by small protein conjugation or removal →	+0.055	+0.106	<.001	<.001	3	17
UCEC	Regulation of signal transduction by p53 class mediator →	+0.054	+0.108	<.001	.001	3	17
STAD	Rhythmic process →	+0.040	+0.088	<.001	<.001	3	16
UCEC	Cellular response to heat →	+0.053	+0.084	<.001	.002	3	16
UCEC	DNA biosynthetic process →	+0.054	+0.061	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,273 associations by consensus.

Exploration

TGFA-IT1 survival (RNA) · tumor vs normal (RNA) · all TGFA-IT1 data types