TFR2

Across TCGA patient cohorts, TFR2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,523 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TFR2-associated proteins across cancer lineages are PUS7, UCK2, and UTP25. Each is linked with TFR2 in more than 4 cancer types. Because this analysis shows association rather than direction, both TFR2-to-partner and partner-to-TFR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TFR2 versus PUS7 in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TFR2→partner) and Y-score (partner→TFR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PUS7 →	+0.521	+0.879	<.001	<.001	3	5
BRCA	UCK2 →	+0.301	+0.704	.001	.001	3	5
HNSC	UTP25 →	+0.356	+0.499	<.001	.002	3	4
GBM	POLD1 →	+0.327	+0.703	<.001	.003	3	4
LSCC	POLR1A →	+0.343	+0.641	<.001	<.001	3	4
LSCC	SUPT16H →	+0.429	+0.609	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,523 associations by consensus.

TFR2 vs PUS7 — BRCA

Explore this scatter interactively →