TFIP11

Across TCGA pan-cancer cohorts, TFIP11 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated TFIP11 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher TFIP11 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TFIP11 expression acts as an unfavorable survival marker, although some lineages such as LSCC and GBM show a favorable association.

CCRCC, HNSC, and LSCC are the cancer types where TFIP11 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	0.699	0.912	.001	37	view →
HNSC	DFS	Tertile	III,IV	0.681	0.940	.011	17	view →
LSCC	DFS	Median	All	0.972	0.906	.006	16	view →
GBM	OS	Median	All	0.445	0.303	.034	4	view →
LUAD	OS	Tertile	III,IV	0.848	0.296	.015	4	view →
UCEC	DFS	Median	All	1.000	0.936	.021	2	view →
PDAC	OS	Tertile	III,IV	0.905	0.621	.038	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

TFIP11–CCRCC (DFS)

Open the CCRCC breakdown →