TFIP11

Across TCGA pan-cancer cohorts, TFIP11 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of TFIP11’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where TFIP11 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TFIP11 is over-expressed in tumor, although a few such as THCA and KIRP show the opposite, repressed pattern.

HNSC, THCA, and LIHC are the cancer types where TFIP11 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TFIP11 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.654	<.001	11	view →
THCA	Male	II,III,IV	−0.615	<.001	10	view →
LIHC	Male	All	+0.979	<.001	9	view →
BLCA	Male	All	+0.456	.010	6	view →
CHOL	Male	All	+1.528	<.001	5	view →
LUSC	Male	All	+0.537	<.001	5	view →
KICH	Male	II,III,IV	+0.752	.001	4	view →
STAD	All	II,III,IV	+0.525	.004	4	view →
KIRC	All	All	+0.200	.003	3	view →
READ	All	III,IV	+0.390	.040	2	view →
KIRP	All	All	−0.337	.014	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

TFIP11–HNSC

Open the HNSC breakdown →