TFF3

Across TCGA cell cohorts, TFF3 RNA expression is significantly associated with the RNA expression of many other genes, with 9,225 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TFF3-associated genes across cancer lineages are TFF1, TOX3, and TMPRSS2. Each is linked with TFF3 in more than 10 cancer types. Because this analysis shows association rather than direction, both TFF3-to-partner and partner-to-TFF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TFF3 versus TFF1 in BREAST, with a Pearson correlation of 0.91.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TFF3→partner) and Y-score (partner→TFF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	TFF1 →	+7.223	+6.144	<.001	<.001	3	11
LUNG_SCLC	TOX3 →	+3.643	+4.121	<.001	<.001	3	8
STOMACH	TMPRSS2 →	+2.901	+2.679	<.001	<.001	3	7
STOMACH	CEACAM5 →	+5.165	+3.847	<.001	<.001	2	8
STOMACH	AGR2 →	+7.641	+3.531	<.001	<.001	3	7
LUNG_SCLC	ATP2A3 →	+3.456	+4.676	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,225 associations by consensus.

TFF3 vs TFF1 — BREAST

Explore this scatter interactively →