TFF3

Across TCGA cell cohorts, TFF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,502 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TFF3-associated GO terms across cancer lineages are Detoxification of copper ion, Stress response to copper ion, and Regulation of somitogenesis. Each is linked with TFF3 in more than 9 cancer types. Because this analysis shows association rather than direction, both TFF3-to-partner and partner-to-TFF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Detoxification of copper ion grouped by TFF3-low versus TFF3-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TFF3→partner) and Y-score (partner→TFF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Detoxification of copper ion →	-0.290	-3.011	.001	.003	2	10
LARGE_INTESTINE	Stress response to copper ion →	-0.290	-3.011	.001	.003	2	10
LUNG_SCLC	Regulation of somitogenesis →	+1.239	+3.976	<.001	<.001	3	8
STOMACH	Receptor-mediated endocytosis of virus by host cell →	-0.209	-2.823	<.001	<.001	3	8
STOMACH	Regulation of entry of bacterium into host cell →	-0.191	-3.382	<.001	<.001	3	8
STOMACH	Cellular response to copper ion →	-0.203	-2.810	.001	.007	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,502 associations by consensus.

Detoxification of copper ion by TFF3 expression — LARGE_INTESTINE

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