TFDP3

Across TCGA patient cohorts, TFDP3 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TFDP3-associated genes across cancer lineages are JAB1, MYH11, and p90 RSK. Each is linked with TFDP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TFDP3-to-partner and partner-to-TFDP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JAB1 grouped by TFDP3-low versus TFDP3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TFDP3→partner) and Y-score (partner→TFDP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	JAB1 →	+0.260	+3.000	.007	.033	3	1
SKCM	MYH11 →	-0.872	-2.000	.023	.031	3	1
SKCM	p90 RSK →	+0.243	+2.000	.009	.031	3	1
SKCM	PI3K-p85 →	+0.210	+3.012	.026	.018	3	1
SKCM	YB-1_pS102 →	-0.168	-2.700	.028	.006	3	1
SKCM	Bid →	-0.158	-3.169	.038	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

JAB1 by TFDP3 expression — SKCM

Explore this box plot interactively →