TFDP3

Across TCGA pan-cancer cohorts, TFDP3 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated TFDP3 data layer compared with 3 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher TFDP3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TFDP3 expression acts as an unfavorable survival marker, although some lineages such as OV and ESCA show a favorable association.

KIRC, OV, and ESCA are the cancer types where TFDP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	III,IV	0.237	0.497	<.001	132	view →
OV	DFS	Quartile	All	0.633	0.522	.008	36	view →
ESCA	OS	Quartile	III,IV	0.652	0.302	.009	25	view →
KICH	OS	Tertile	II,III,IV	0.346	0.843	.006	24	view →
SCLC	DFS	Tertile	III,IV	0.137	0.756	.025	18	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
UCEC	DFS	Quartile	All	0.772	0.867	.004	12	view →
THYM	DFS	Quartile	All	1.000	0.516	.011	10	view →
THCA	OS	Tertile	IV	0.790	1.000	.016	9	view →
BRCA	DFS	Tertile	IV	0.691	0.340	.015	9	view →
LIHC	OS	Tertile	II,III,IV	0.338	0.485	.032	8	view →
LUAD	DFS	Tertile	III,IV	0.797	0.559	.036	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

TFDP3–KIRC (DFS)

Open the KIRC breakdown →