TFB2M

Across TCGA patient cohorts, TFB2M protein abundance is significantly associated with the RNA expression of many other genes, with 18,129 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TFB2M-associated genes across cancer lineages are CNRIP1, MS4A2, and IFFO1. Each is linked with TFB2M in more than 8 cancer types. Because this analysis shows association rather than direction, both TFB2M-to-partner and partner-to-TFB2M results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TFB2M versus CNRIP1 in CCRCC, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TFB2M→partner) and Y-score (partner→TFB2M) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CNRIP1 →	-0.889	-0.410	<.001	<.001	3	9
BRCA	MS4A2 →	-1.070	-0.446	<.001	<.001	3	9
BRCA	IFFO1 →	-0.614	-0.428	<.001	<.001	3	8
OV	MAGI2-AS3 →	-0.965	-0.580	<.001	<.001	3	8
BRCA	CPA3 →	-1.615	-0.424	<.001	<.001	3	8
OV	CD33 →	-0.714	-0.571	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,129 associations by consensus.

TFB2M vs CNRIP1 — CCRCC

Explore this scatter interactively →