TFB2M

Across TCGA cell cohorts, TFB2M RNA expression is significantly associated with the go_rna of many other GO terms, with 3,807 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TFB2M-associated GO terms across cancer lineages are Positive regulation of rRNA processing, Nuclear pore organization, and Ribosomal large subunit biogenesis. Each is linked with TFB2M in more than 16 cancer types. Because this analysis shows association rather than direction, both TFB2M-to-partner and partner-to-TFB2M results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of rRNA processing grouped by TFB2M-low versus TFB2M-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TFB2M→partner) and Y-score (partner→TFB2M) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of rRNA processing →	+0.123	+0.753	<.001	<.001	3	17
BONE	Nuclear pore organization →	+0.173	+0.747	<.001	<.001	3	17
BONE	Ribosomal large subunit biogenesis →	+0.130	+0.758	<.001	<.001	3	16
BONE	Ribosomal large subunit assembly →	+0.139	+1.080	.002	<.001	3	16
BONE	Nuclear pore complex assembly →	+0.142	+0.814	<.001	<.001	3	16
OVARY	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.111	+0.762	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,807 associations by consensus.

Positive regulation of rRNA processing by TFB2M expression — LUNG_SCLC

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