TFAP2D

Across TCGA patient cohorts, TFAP2D RNA expression is significantly associated with the go_rna of many other GO terms, with 6,842 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TFAP2D-associated GO terms across cancer lineages are Mitotic nuclear division, Sister chromatid segregation, and Chromosome localization. Each is linked with TFAP2D in more than 12 cancer types. Because this analysis shows association rather than direction, both TFAP2D-to-partner and partner-to-TFAP2D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic nuclear division grouped by TFAP2D-low versus TFAP2D-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TFAP2D→partner) and Y-score (partner→TFAP2D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitotic nuclear division →	+0.075	+0.148	<.001	<.001	3	13
STAD	Sister chromatid segregation →	+0.079	+0.163	<.001	<.001	3	13
STAD	Chromosome localization →	+0.077	+0.153	<.001	<.001	3	12
STAD	Spindle assembly →	+0.074	+0.160	<.001	<.001	3	12
ESCA	DNA replication →	+0.074	+0.165	<.001	.001	2	13
ESCA	Spindle organization →	+0.075	+0.184	<.001	.001	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,842 associations by consensus.

Mitotic nuclear division by TFAP2D expression — STAD

Explore this box plot interactively →