TFAP2C

Across TCGA patient cohorts, TFAP2C RNA expression is significantly associated with the protein abundance of many other proteins, with 13,627 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TFAP2C-associated proteins across cancer lineages are TFAP2C_S434, GRHL1_T208, and STAU1. Each is linked with TFAP2C in more than 4 cancer types. Because this analysis shows association rather than direction, both TFAP2C-to-partner and partner-to-TFAP2C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TFAP2C versus TFAP2C_S434 in LSCC, with a Pearson correlation of 0.79.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TFAP2C→partner) and Y-score (partner→TFAP2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TFAP2C_S434 →	+0.995	+1.136	<.001	<.001	3	5
BRCA	GRHL1_T208 →	+1.132	+1.236	<.001	<.001	3	5
HNSC	STAU1 →	+0.225	+0.620	<.001	.006	3	4
LSCC	NECTIN4 →	+0.597	+0.908	<.001	<.001	3	4
LUAD	ATP2A3 →	-0.676	-1.039	<.001	<.001	3	4
LUAD	CEP164_S407 →	-0.479	-0.876	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,627 associations by consensus.

TFAP2C vs TFAP2C_S434 — LSCC

Explore this scatter interactively →