TF

Across TCGA cell cohorts, TF RNA expression is significantly associated with the go_rna of many other GO terms, with 2,123 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible TF-associated GO terms across cancer lineages are Mitochondrial electron transport, cytochrome c to oxygen, Negative regulation of myoblast fusion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with TF in more than 7 cancer types. Because this analysis shows association rather than direction, both TF-to-partner and partner-to-TF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial electron transport, cytochrome c to oxygen grouped by TF-low versus TF-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TF→partner) and Y-score (partner→TF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Mitochondrial electron transport, cytochrome c to oxygen →	+0.077	+0.520	.003	.005	3	8
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.105	+0.350	.001	.005	3	7
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.101	+0.350	.001	.005	2	8
LUNG_NSCLC_LUSC	Response to starvation →	+0.040	+0.248	.003	.001	3	7
SKIN	Regulation of mitophagy →	+0.099	+3.458	<.001	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.090	+0.332	.002	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,123 associations by consensus.

Mitochondrial electron transport, cytochrome c to oxygen by TF expression — OVARY

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