Across TCGA patient cohorts, TEX43 mutation is significantly associated with the RNA expression of many other genes, with 72 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEX43-associated genes across cancer lineages are MT1CP, RN7SL248P, and MIR5681A. Each is linked with TEX43 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX43-to-partner and partner-to-TEX43 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX43→partner) and Y-score (partner→TEX43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MT1CP →	+0.349	+3.695	<.001	.009	3	2
UCEC	RN7SL248P →	+0.118	+4.400	<.001	.006	3	1
BLCA	MIR5681A →	+0.483	+7.640	<.001	.009	3	1
BLCA	OPN1MW →	+0.039	+7.640	<.001	.009	3	1
UCEC	SSTR5 →	+0.822	+3.506	.001	.007	3	1
UCEC	C11orf40 →	+0.218	+3.204	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 72 associations by consensus.

Exploration

TEX43 survival (RNA) · tumor vs normal (RNA) · all TEX43 data types