TEX37

Across TCGA patient cohorts, TEX37 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEX37-associated genes across cancer lineages are Notch1, PDCD4, and Tuberin. Each is linked with TEX37 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX37-to-partner and partner-to-TEX37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by TEX37-low versus TEX37-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX37→partner) and Y-score (partner→TEX37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.313	+3.009	<.001	.019	3	1
UCEC	PDCD4 →	-0.607	-2.990	.018	.036	3	1
UCEC	Tuberin →	+0.306	+3.009	.039	.019	3	1
UCEC	Rab25 →	-0.488	-3.169	.007	.020	2	1
UCEC	S6_pS240_S244 →	+0.574	+3.169	.010	.020	1	1
UCEC	TFRC →	+0.822	+3.169	.004	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Notch1 by TEX37 expression — UCEC

Explore this box plot interactively →