TEX261

Across TCGA patient cohorts, TEX261 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEX261-associated genes across cancer lineages are mv Endothelial cells, lymphatic Endothelial cells, and Plasma cells. Each is linked with TEX261 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX261-to-partner and partner-to-TEX261 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mv Endothelial cells grouped by TEX261-low versus TEX261-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX261→partner) and Y-score (partner→TEX261) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mv Endothelial cells →	-0.035	-3.169	.007	.019	3	1
UCEC	lymphatic Endothelial cells →	-0.028	-3.116	.031	.020	2	1
UCEC	Plasma cells →	-0.025	-3.127	.034	.020	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

mv Endothelial cells by TEX261 expression — UCEC

Explore this box plot interactively →