TEX26

Across TCGA patient cohorts, TEX26 mutation is significantly associated with the RNA expression of many other genes, with 420 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEX26-associated genes across cancer lineages are RNU6-1183P, MIR760, and KCND3-IT1. Each is linked with TEX26 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX26-to-partner and partner-to-TEX26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1183P grouped by TEX26-low versus TEX26-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX26→partner) and Y-score (partner→TEX26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-1183P →	+0.236	+3.009	<.001	.009	3	2
UCEC	MIR760 →	+0.499	+2.182	<.001	.007	3	2
BLCA	KCND3-IT1 →	+0.100	+3.320	.002	.008	3	2
UCEC	DPP9 →	+0.546	+3.617	<.001	.001	3	2
BRCA	FAM236A →	+0.066	+8.057	<.001	.005	3	1
BRCA	SPATA31A5 →	+0.006	+7.471	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 420 associations by consensus.

RNU6-1183P by TEX26 expression — SKCM

Explore this box plot interactively →