TEX26

Across TCGA pan-cancer cohorts, TEX26 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of TEX26’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where TEX26 RNA is repressed in tumor relative to normal tissue. In most cancer types TEX26 is over-expressed in tumor, although a few such as LIHC and KIRC show the opposite, repressed pattern.

LIHC, KIRC, and BRCA are the cancer types where TEX26 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TEX26 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	III,IV	−0.393	<.001	9	view →
KIRC	All	All	−0.037	<.001	7	view →
BRCA	All	III,IV	−0.430	<.001	6	view →
KICH	All	II,III,IV	−0.066	.002	6	view →
LUSC	All	All	−0.586	<.001	5	view →
STAD	All	All	−0.212	<.001	4	view →
PRAD	All	All	−0.407	<.001	2	view →
COAD	All	All	−0.038	.038	2	view →
READ	Female	All	−0.120	.007	1	view →
THCA	Male	All	−0.030	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

TEX26–LIHC

Open the LIHC breakdown →