TEX26

Across TCGA patient cohorts, TEX26 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEX26-associated genes across cancer lineages are NDRG1_pT346, Myosin-IIa_pS1943, and Myosin-IIa. Each is linked with TEX26 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX26-to-partner and partner-to-TEX26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NDRG1_pT346 grouped by TEX26-low versus TEX26-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX26→partner) and Y-score (partner→TEX26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NDRG1_pT346 →	-0.555	-3.321	.030	.010	3	2
UCEC	Myosin-IIa_pS1943 →	+0.295	+3.335	.006	.005	3	1
UCEC	Myosin-IIa →	+0.286	+2.177	.003	.035	3	1
UCEC	Paxillin →	+0.272	+2.817	.045	.036	3	1
UCEC	Annexin-1 →	+0.761	+3.321	.005	.010	3	1
UCEC	VEGFR2 →	+0.504	+2.179	.001	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

NDRG1_pT346 by TEX26 expression — UCEC

Explore this box plot interactively →