TEX26

Across TCGA cell cohorts, TEX26 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible TEX26-associated genes across cancer lineages are COL6A5, SPINK8, and MROH2B. Each is linked with TEX26 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX26-to-partner and partner-to-TEX26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COL6A5 grouped by TEX26-low versus TEX26-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX26→partner) and Y-score (partner→TEX26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	COL6A5 →	+0.065	+3.760	<.001	.008	3	1
LUNG_NSCLC_LUAD	SPINK8 →	+0.526	+4.813	<.001	<.001	3	1
LARGE_INTESTINE	MROH2B →	+0.006	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

COL6A5 by TEX26 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →