Across TCGA patient cohorts, TEX22 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEX22-associated genes across cancer lineages are RN7SL248P, RNU6-1029P, and RNU6-1077P. Each is linked with TEX22 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX22-to-partner and partner-to-TEX22 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX22→partner) and Y-score (partner→TEX22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.222	+5.722	<.001	.001	3	1
UCEC	RNU6-1029P →	+0.752	+5.386	<.001	.001	3	1
UCEC	RNU6-1077P →	+1.189	+4.188	<.001	.009	3	1
UCEC	LIPT1P1 →	+0.111	+5.123	<.001	.004	3	1
UCEC	LINC02644 →	+0.363	+4.484	<.001	.009	3	1
UCEC	SLC25A5P4 →	+0.305	+4.398	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

TEX22 survival (RNA) · tumor vs normal (RNA) · all TEX22 data types