TEX15

Across TCGA cell cohorts, TEX15 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,488 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TEX15-associated GO terms across cancer lineages are DNA-templated transcription initiation, Protein-DNA complex organization, and Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with TEX15 in more than 10 cancer types. Because this analysis shows association rather than direction, both TEX15-to-partner and partner-to-TEX15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by TEX15-low versus TEX15-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX15→partner) and Y-score (partner→TEX15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated transcription initiation →	+0.072	+1.413	<.001	<.001	3	11
BONE	Protein-DNA complex organization →	+0.067	+1.552	<.001	<.001	3	11
BONE	Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.107	+1.400	<.001	<.001	3	11
BONE	Regulation of DNA replication →	+0.086	+1.636	.003	<.001	3	10
BONE	Nucleocytoplasmic transport →	+0.090	+1.910	<.001	<.001	3	10
BONE	rRNA metabolic process →	+0.118	+1.804	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,488 associations by consensus.

DNA-templated transcription initiation by TEX15 expression — BONE

Explore this box plot interactively →