TEX15

Across TCGA pan-cancer cohorts, TEX15 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of TEX15’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TEX15 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TEX15 is over-expressed in tumor, although a few such as COAD and UCEC show the opposite, repressed pattern.

KIRC, HNSC, and LUAD are the cancer types where TEX15 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TEX15 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	III,IV	+1.346	<.001	11	view →
HNSC	Male	II,III,IV	+0.416	.012	4	view →
LUAD	All	All	+0.326	.001	4	view →
LUSC	Male	All	+0.318	.006	4	view →
KIRP	All	II,III,IV	+0.326	.029	3	view →
COAD	Female	II,III,IV	−0.008	.002	3	view →
UCEC	All	All	−1.613	<.001	2	view →
BRCA	Female	All	+0.043	.044	2	view →
STAD	Female	III,IV	−0.155	.040	1	view →
THCA	All	All	−0.005	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

TEX15–KIRC

Open the KIRC breakdown →