TEX15

Across TCGA cell cohorts, TEX15 mutation is significantly associated with the RNA expression of many other genes, with 354 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TEX15-associated genes across cancer lineages are ZP4, POC1A, and OR4X2. Each is linked with TEX15 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX15-to-partner and partner-to-TEX15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZP4 grouped by TEX15-low versus TEX15-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX15→partner) and Y-score (partner→TEX15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	ZP4 →	+0.069	+2.781	<.001	.002	3	2
SOFT_TISSUE	POC1A →	+0.653	+3.169	.008	.005	3	2
SOFT_TISSUE	OR4X2 →	+0.014	+3.369	<.001	.001	3	2
SOFT_TISSUE	ARL13A →	+0.164	+3.206	.002	.001	3	2
SOFT_TISSUE	SPANXA2 →	+2.077	+2.774	<.001	.005	3	2
OESOPHAGUS	SSX3 →	+0.044	+3.392	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 354 associations by consensus.

ZP4 by TEX15 expression — SOFT_TISSUE

Explore this box plot interactively →