TEX13B

Across TCGA patient cohorts, TEX13B mutation is significantly associated with the RNA expression of many other genes, with 2,676 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEX13B-associated genes across cancer lineages are MANEAL, FANCG, and ACTG1P23. Each is linked with TEX13B in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX13B-to-partner and partner-to-TEX13B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MANEAL grouped by TEX13B-low versus TEX13B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX13B→partner) and Y-score (partner→TEX13B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MANEAL →	+0.948	+2.721	<.001	.003	3	2
UCEC	FANCG →	+0.475	+2.095	.001	.003	3	2
UCEC	ACTG1P23 →	+0.223	+1.818	.008	.002	3	2
UCEC	RPL32P32 →	+0.421	+1.860	<.001	.002	3	2
SKCM	DMRTC1 →	+0.011	+4.054	<.001	.001	3	2
SKCM	LINC02348 →	+0.145	+3.038	.006	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,676 associations by consensus.

MANEAL by TEX13B expression — UCEC

Explore this box plot interactively →