TEX13B

Across TCGA patient cohorts, TEX13B mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEX13B-associated genes across cancer lineages are A-Raf_pS299, JNK2, and MEK1. Each is linked with TEX13B in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX13B-to-partner and partner-to-TEX13B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, A-Raf_pS299 grouped by TEX13B-low versus TEX13B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX13B→partner) and Y-score (partner→TEX13B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.097	-3.584	.024	.002	3	2
UCEC	JNK2 →	+0.240	+3.727	<.001	<.001	3	2
UCEC	MEK1 →	+0.541	+2.807	<.001	<.001	3	2
UCEC	p62 Lck ligand →	+0.244	+1.884	.037	.030	3	2
UCEC	PKC-a_pS657 →	+0.284	+1.293	.038	.037	3	2
UCEC	Chk2 →	-0.350	-3.087	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

A-Raf_pS299 by TEX13B expression — UCEC

Explore this box plot interactively →