TEX10

Across TCGA pan-cancer cohorts, TEX10 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TEX10 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher TEX10 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TEX10 expression acts as an unfavorable survival marker, although some lineages such as LSCC and HNSC show a favorable association.

PDAC, LSCC, and HNSC are the cancer types where TEX10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	All	0.295	0.524	.007	15	view →
LSCC	DFS	Median	II,III,IV	0.848	0.549	.009	7	view →
HNSC	OS	Median	III,IV	0.777	0.555	.012	5	view →
LUAD	DFS	Quartile	All	0.675	1.000	.032	1	view →
CCRCC	OS	Median	II,III,IV	1.000	0.449	.032	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TEX10–PDAC (OS)

Open the PDAC breakdown →