TEX10

Across TCGA pan-cancer cohorts, TEX10 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of TEX10’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where TEX10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TEX10 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

COAD, HNSC, and STAD are the cancer types where TEX10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TEX10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	IV	+1.346	<.001	11	view →
HNSC	Male	IV	+1.259	<.001	11	view →
STAD	Male	II,III,IV	+0.896	<.001	9	view →
LIHC	Female	II,III,IV	+0.823	<.001	8	view →
THCA	All	II,III,IV	−0.461	<.001	8	view →
READ	All	All	+1.001	<.001	7	view →
LUSC	Male	II,III,IV	+1.014	<.001	6	view →
ESCA	All	All	+0.985	<.001	5	view →
KICH	Female	All	−0.954	<.001	5	view →
CHOL	Male	All	+1.965	<.001	4	view →
LUAD	All	All	+0.255	.001	3	view →
UCEC	All	IV	−1.145	.008	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

TEX10–COAD

Open the COAD breakdown →