TEX10

Across TCGA patient cohorts, TEX10 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEX10-associated genes across cancer lineages are ATM, eEF2, and INPP4B. Each is linked with TEX10 in more than 2 cancer types. Because this analysis shows association rather than direction, both TEX10-to-partner and partner-to-TEX10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by TEX10-low versus TEX10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX10→partner) and Y-score (partner→TEX10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.526	-1.807	<.001	<.001	3	3
UCEC	eEF2 →	+0.233	+1.184	.028	.022	3	2
UCEC	INPP4B →	-0.255	-2.584	.008	<.001	3	2
UCEC	p27_pT198 →	+0.091	+2.087	.004	.005	3	2
UCEC	VHL →	-0.753	-1.847	<.001	.007	3	2
UCEC	EGFR →	-0.176	-1.584	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

ATM by TEX10 expression — UCEC

Explore this box plot interactively →