TEX10

Across TCGA cell cohorts, TEX10 mutation is significantly associated with the RNA expression of many other genes, with 323 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TEX10-associated genes across cancer lineages are RNF133, OR2AG1, and SULT2A1. Each is linked with TEX10 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX10-to-partner and partner-to-TEX10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNF133 grouped by TEX10-low versus TEX10-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX10→partner) and Y-score (partner→TEX10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	RNF133 →	+0.057	+3.536	<.001	.001	3	2
BLOOD_Leukemia	OR2AG1 →	+0.086	+3.540	.001	.005	3	2
BLOOD_Myeloma	SULT2A1 →	+0.110	+4.807	<.001	.006	3	1
BLOOD_Myeloma	C16orf78 →	+0.053	+4.807	<.001	.006	3	1
BLOOD_Leukemia	NLRP14 →	+0.152	+3.409	<.001	.008	3	1
BLOOD_Leukemia	TLX3 →	+1.941	+3.266	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 323 associations by consensus.

RNF133 by TEX10 expression — BLOOD_Leukemia

Explore this box plot interactively →